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Home > Products >  Milrinone

Milrinone CAS NO.78415-72-2

  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,Other
  • Product Details

Keywords

  • 78415-72-2
  • Milrinone
  • C12H9N3O

Quick Details

  • ProName: Milrinone
  • CasNo: 78415-72-2
  • Molecular Formula: C12H9N3O
  • Appearance: white powder
  • Application: congestive heart failure unresponsive
  • DeliveryTime: in 5-7days
  • PackAge: 1KG/aluminum bags or as your requires
  • ProductionCapacity: 500 Kilogram/Month
  • Purity: 99.8%
  • Storage: dry and cool place
  • Transportation: delivery: ems/ eub/ usps/ ups/ tnt/ fe...
  • LimitNum: 1 Kilogram

Superiority

  • ProName: High quality Milrinone with best price
  • CasNo: 78415-72-2
  • Molecular Formula: C12H9N3O
  • Appearance: Almost white crystalline powder
  • Application: congestive heart failure unresponsive ...
  • DeliveryTime: within in 5-7 working days after recei...
  • PackAge: 5kg/barrel or as customers' requiremen...
  • Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
  • ProductionCapacity: 200 Kilogram/Month
  • Purity: ≥99.8%
  • Storage: Stored as directed away from heat and ...
  • Transportation: by sea/by express
  • LimitNum: 10 Gram
  • Residue on Ignition: ≤0.1%
  • Valid Period: Two years

Details

name

milrinone

type

small molecule

melting point

>300 °c

water solubility

slightly soluble

groups

approved

description

a positive inotropic cardiotonic agent with vasodilator properties. it inhibits camp phosphodiesterase activity in myocardium and vascular smooth muscle. milrinone is a derivative of amrinone and has 20-30 times the ionotropic potency of amrinone. [pubchem]

structure

thumb

pharmacology

indication

indicated for the treatment of congestive heart failure.

pharmacodynamics

milrinone, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

mechanism of action

milrinone inhibits erythrocyte phosphodiesterase, resulting in an increase in erythrocyte camp activity. subsequently, the erythrocyte membrane becomes more resistant to deformity. along with erythrocyte activity, milrinone also decreases blood viscosity by reducing plasma fibrinogen concentrations and increasing fibrinolytic activity.

absorption

milrinone is rapidly and almost completely absorbed after oral administration. bioavailability is 92% (in healthy volunteers).

we are professional mdpt manufacturer in china

we have many customers purchase big quantity from us monthly.

all chemicals we sell are best quality and competitive price. 

we delivery parcels by tnt and ems and dhl and fedex and ups

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about us:

kern Enterprises Co. LTD., is a large group corporation which engaged in the r&d and manufacture of chemicals, pharmaceuticals and intermediates. we have earned ourselves a good reputation at home and abroad with advanced technology, standardized management and well established service systerm. we have developed to a very famous group corporation enterprise in chemical industry step by step.

 

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